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Cerebrotendinous xanthomatosis: a defect in mitochondrial 26-hydroxylation required for normal biosynthesis of cholic acid.

Oxidation of side chain of 5 beta-cholestane-3 alpha,7 alpha,12 alpha-triol was studied in a patient with cerebrotendinous xanthomatosis (CTX) and in control subjects, using various subcellular fractions of liver homogenate and a method based on isotope dilution-mass spectrometry. In the control, 5...

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Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Oftebro, H, Björkhem, I, Skrede, S, Schreiner, A, Pederson, J I
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 1980
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371480/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7410549/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109806
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