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Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects.

To assess the mechanisms of the insulin resistance in human obesity, we have determined, using a modification of the euglycemic glucose clamp technique, the shape of the in vivo insulin-glucose disposal dose-response curves in 7 control and 13 obese human subjects. Each subject had at least three eu...

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Библиографические подробности
Главные авторы: Kolterman, O G, Insel, J, Saekow, M, Olefsky, J M
Формат: Artigo
Язык:Inglês
Опубликовано: 1980
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC371464/
https://ncbi.nlm.nih.gov/pubmed/6997333
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