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RIG-I activation inhibits HIV replication in macrophages
The RIG-I signaling pathway is critical in the activation of the type I IFN-dependent antiviral innate-immune response. We thus examined whether RIG-I activation can inhibit HIV replication in macrophages. We showed that the stimulation of monocyte-derived macrophages with 5′ppp-dsRNA, a synthetic l...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Leukocyte Biology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3714567/ https://ncbi.nlm.nih.gov/pubmed/23744645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0313158 |
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