Increases in cerebrospinal fluid caffeine concentration are associated with favorable outcome after severe traumatic brain injury in humans

Caffeine, the most widely consumed psychoactive drug and a weak adenosine receptor antagonist, can be neuroprotective or neurotoxic depending on the experimental model or neurologic disorder. However, its contribution to pathophysiology and outcome in traumatic brain injury (TBI) in humans is undefi...

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Main Authors: Sachse, Kathleen T, Jackson, Edwin K, Wisniewski, Stephen R, Gillespie, Delbert G, Puccio, Ava M, Clark, Robert SB, Dixon, C Edward, Kochanek, Patrick M
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714395/
https://ncbi.nlm.nih.gov/pubmed/17684518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jcbfm.9600539
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