Effect of Short Periods of Normobaric Hyperoxia on Local Brain Tissue Oxygenation and Cerebrospinal Fluid Oxidative Stress Markers in Severe Traumatic Brain Injury

Preliminary evidence suggests local brain tissue oxygenation (PbtO(2)) values of ≤15 mm Hg following severe traumatic brain injury (TBI) represent brain tissue hypoxia. Accordingly, many neurotrauma units attempt to maintain PbtO(2) ≥20 mm Hg to avoid hypoxia. This study tested the impact of a short...

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Main Authors: Puccio, Ava M., Hoffman, Leslie A., Bayir, Hülya, Zullo, Thomas G., Fischer, Michael, Darby, Joseph, Alexander, Sheila, Dixon, C. Edward, Okonkwo, David O., Kochanek, Patrick M.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2009
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850254/
https://ncbi.nlm.nih.gov/pubmed/19505175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2008.0624
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