Effect of Short Periods of Normobaric Hyperoxia on Local Brain Tissue Oxygenation and Cerebrospinal Fluid Oxidative Stress Markers in Severe Traumatic Brain Injury

Preliminary evidence suggests local brain tissue oxygenation (PbtO(2)) values of ≤15 mm Hg following severe traumatic brain injury (TBI) represent brain tissue hypoxia. Accordingly, many neurotrauma units attempt to maintain PbtO(2) ≥20 mm Hg to avoid hypoxia. This study tested the impact of a short...

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Autors principals: Puccio, Ava M., Hoffman, Leslie A., Bayir, Hülya, Zullo, Thomas G., Fischer, Michael, Darby, Joseph, Alexander, Sheila, Dixon, C. Edward, Okonkwo, David O., Kochanek, Patrick M.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2009
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850254/
https://ncbi.nlm.nih.gov/pubmed/19505175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2008.0624
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