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N-cadherin haploinsufficiency increases survival in a mouse model of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDA) is often detected at a late stage, hence the identification of new therapies that have potential to block tumor progression is critical for this lethal disease. N-cadherin upregulation has been observed in many cancers including PDA, however a causal role for t...

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Detalhes bibliográficos
Main Authors: Su, Yanrong, Li, Jifen, Witkiewicz, Agnieszka K., Brennan, Donna, Neill, Thomas, Talarico, Jennifer, Radice, Glenn L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714178/
https://ncbi.nlm.nih.gov/pubmed/22158044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.574
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