Molecular interactions of ErbB1 (EGFR) and integrin-β1 in astrocytoma frozen sections predict clinical outcome and correlate with Akt-mediated in vitro radioresistance

INTRODUCTION: Treatment of astrocytoma is frequently hampered by radioresistance of the tumor. In addition to overexpression of ErbB1/EGFR, functional crosstalk between receptor tyrosine kinases and cell adhesion molecules may also contribute to therapy resistance. METHODS: Acceptor photobleaching F...

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Bibliografiske detaljer
Main Authors: Petrás, Miklós, Lajtos, Tamás, Friedländer, Elza, Klekner, Álmos, Pintye, Éva, Feuerstein, Burt G., Szöllősi, János, Vereb, György
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Basic and Translational Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714153/
https://ncbi.nlm.nih.gov/pubmed/23595626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not046
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