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Sulfonyl 3-alkynyl pantetheinamides as mechanism-based crosslinkers of ACP dehydratase

The acyl carrier protein (ACP) plays a central function in acetate biosynthetic pathways, serving as a tether for substrates and growing intermediates. Activity and structural studies have highlighted the complexities of this role, and its protein-protein interactions have recently come under scruti...

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Detalhes bibliográficos
Main Authors: Ishikawa, Fumihiro, Haushalter, Robert W., Lee, D. John, Finzel, Kara, Burkart, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713789/
https://ncbi.nlm.nih.gov/pubmed/23718183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4042059
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