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Random and Site-Specific Mutagenesis of the Helicobacter pylori Ferric Uptake Regulator Provides Insight into Fur Structure-Function Relationships

The ferric uptake regulator (Fur) of Helicobacter pylori is a global regulator that is important for colonization and survival within the gastric mucosa. H. pylori Fur is unique in its ability to activate and repress gene expression in both the iron-bound (Fe-Fur) and apo forms (apo-Fur). In the cur...

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Bibliografiske detaljer
Main Authors: Gilbreath, Jeremy J., Pich, Oscar Q., Benoit, Stéphane L., Besold, Angelique N., Cha, Jeong-Heon, Maier, Robert J., Michel, Sarah L.J., Maynard, Ernest L., Merrell, D. Scott
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713617/
https://ncbi.nlm.nih.gov/pubmed/23710935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12278
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