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Random and Site-Specific Mutagenesis of the Helicobacter pylori Ferric Uptake Regulator Provides Insight into Fur Structure-Function Relationships

The ferric uptake regulator (Fur) of Helicobacter pylori is a global regulator that is important for colonization and survival within the gastric mucosa. H. pylori Fur is unique in its ability to activate and repress gene expression in both the iron-bound (Fe-Fur) and apo forms (apo-Fur). In the cur...

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Detalhes bibliográficos
Main Authors: Gilbreath, Jeremy J., Pich, Oscar Q., Benoit, Stéphane L., Besold, Angelique N., Cha, Jeong-Heon, Maier, Robert J., Michel, Sarah L.J., Maynard, Ernest L., Merrell, D. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713617/
https://ncbi.nlm.nih.gov/pubmed/23710935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12278
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