Toll-Like Receptor 9 Promotes Cardiac Inflammation and Heart Failure during Polymicrobial Sepsis

Background. Aim was to elucidate the role of toll-like receptor 9 (TLR9) in cardiac inflammation and septic heart failure in a murine model of polymicrobial sepsis. Methods. Sepsis was induced via colon ascendens stent peritonitis (CASP) in C57BL/6 wild-type (WT) and TLR9-deficient (TLR9-D) mice. Ba...

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Hauptverfasser: Lohner, Ralph, Schwederski, Markus, Narath, Carolin, Klein, Johanna, Duerr, Georg D., Torno, Alexandra, Knuefermann, Pascal, Hoeft, Andreas, Baumgarten, Georg, Meyer, Rainer, Boehm, Olaf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713595/
https://ncbi.nlm.nih.gov/pubmed/23935245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/261049
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