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Conformational Analysis of Recombinant Monoclonal Antibodies with Hydrogen/Deuterium Exchange Mass Spectrometry

Understanding the conformation of antibodies, especially those of therapeutic value, is of great interest. Many of the current analytical methods used to probe protein conformation face issues in the analysis of antibodies, either due to the nature of the antibody itself or the limitations of the me...

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Autores principales: Houde, Damian, Engen, John R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713497/
https://ncbi.nlm.nih.gov/pubmed/23475726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-327-5_17
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