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Conformational Analysis of Recombinant Monoclonal Antibodies with Hydrogen/Deuterium Exchange Mass Spectrometry

Understanding the conformation of antibodies, especially those of therapeutic value, is of great interest. Many of the current analytical methods used to probe protein conformation face issues in the analysis of antibodies, either due to the nature of the antibody itself or the limitations of the me...

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Bibliografske podrobnosti
Main Authors: Houde, Damian, Engen, John R.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713497/
https://ncbi.nlm.nih.gov/pubmed/23475726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-327-5_17
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