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Conformational Analysis of Recombinant Monoclonal Antibodies with Hydrogen/Deuterium Exchange Mass Spectrometry

Understanding the conformation of antibodies, especially those of therapeutic value, is of great interest. Many of the current analytical methods used to probe protein conformation face issues in the analysis of antibodies, either due to the nature of the antibody itself or the limitations of the me...

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Detalles Bibliográficos
Main Authors: Houde, Damian, Engen, John R.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713497/
https://ncbi.nlm.nih.gov/pubmed/23475726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-327-5_17
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