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Kisspeptin Activation of TRPC4 Channels in Female GnRH Neurons Requires PIP(2) Depletion and cSrc Kinase Activation
Kisspeptin signaling via its Gαq-coupled receptor GPR54 plays a crucial role in modulating GnRH neuronal excitability, which controls pituitary gonadotropins secretion and ultimately reproduction. Kisspeptin potently depolarizes GnRH neurons primarily through the activation of canonical transient re...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Endocrine Society
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3713215/ https://ncbi.nlm.nih.gov/pubmed/23744639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1180 |
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