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Kisspeptin inhibits a slow afterhyperpolarization current via protein kinase C and reduces spike frequency adaptation in GnRH neurons

Kisspeptin signaling via its cognate receptor G protein-coupled receptor 54 (GPR54) in gonadotropin-releasing hormone (GnRH) neurons plays a critical role in regulating pituitary secretion of luteinizing hormone and thus reproductive function. GPR54 is G(q)-coupled to activation of phospholipase C a...

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Detalhes bibliográficos
Main Authors: Zhang, Chunguang, Rønnekleiv, Oline K., Kelly, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680681/
https://ncbi.nlm.nih.gov/pubmed/23548613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00058.2013
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