The cell death protease Kex1p is essential for hypochlorite-induced apoptosis in yeast

Following microbial pathogen invasion, the human immune system of activated phagocytes generates and releases the potent oxidant hypochlorous acid (HOCl), which contributes to the killing of menacing microorganisms. Though tightly controlled, HOCl generation by the myeloperoxidase-hydrogen peroxide-...

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Huvudupphovsmän: Carmona-Gutierrez, Didac, Alavian-Ghavanini, Ali, Habernig, Lukas, Bauer, Maria Anna, Hammer, Astrid, Rossmann, Christine, Zimmermann, Andreas S., Ruckenstuhl, Christoph, Büttner, Sabrina, Eisenberg, Tobias, Sattler, Wolfgang, Malle, Ernst, Madeo, Frank
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713129/
https://ncbi.nlm.nih.gov/pubmed/23656787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24801
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