Hypochlorite-modified high-density lipoprotein promotes induction of HO-1 in endothelial cells via activation of p42/44 MAPK and zinc finger transcription factor Egr-1()

Modification/chlorination of high-density lipoprotein (HDL) by hypochlorous acid (HOCl), formed by the myeloperoxidase–H(2)O(2)–chloride system of activated phagocytes, converts an anti-atherogenic lipoprotein into a pro-inflammatory lipoprotein particle. Chlorinated HDL is present in human lesion m...

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Autores principales: Rossmann, Christine, Rauh, Anamaria, Hammer, Astrid, Windischhofer, Werner, Zirkl, Sandra, Sattler, Wolfgang, Malle, Ernst
Formato: Artigo
Lenguaje:Inglês
Publicado: Academic Press 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081070/
https://ncbi.nlm.nih.gov/pubmed/21354100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.02.016
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