Corruption of the Intra-Gene DNA Methylation Architecture Is a Hallmark of Cancer

Epigenetic processes - including DNA methylation - are increasingly seen as having a fundamental role in chronic diseases like cancer. It is well known that methylation levels at particular genes or loci differ between normal and diseased tissue. Here we investigate whether the intra-gene methylatio...

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Bibliografiske detaljer
Main Authors: Bartlett, Thomas E., Zaikin, Alexey, Olhede, Sofia C., West, James, Teschendorff, Andrew E., Widschwendter, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712966/
https://ncbi.nlm.nih.gov/pubmed/23874574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068285
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