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Corruption of the Intra-Gene DNA Methylation Architecture Is a Hallmark of Cancer

Epigenetic processes - including DNA methylation - are increasingly seen as having a fundamental role in chronic diseases like cancer. It is well known that methylation levels at particular genes or loci differ between normal and diseased tissue. Here we investigate whether the intra-gene methylatio...

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Autors principals: Bartlett, Thomas E., Zaikin, Alexey, Olhede, Sofia C., West, James, Teschendorff, Andrew E., Widschwendter, Martin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712966/
https://ncbi.nlm.nih.gov/pubmed/23874574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068285
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