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Metabolism of arachidonic acid in ionophore-stimulated neutrophils. Esterification of a hydroxylated metabolite into phospholipids.

[14C]Arachidonic acid incubated with human neutrophils was esterified into phospholipids and triglycerides. Stimulation of these labeled neutrophils with ionophore A23187 (2 microM) results in release of [14C]arachidonate from phospholipid and its metabolism to prostaglandin E2 and 5-hydroxy-6,8,11,...

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Vydáno v:J Clin Invest
Hlavní autoři: Stenson, W F, Parker, C W
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1979
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371295/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/387819/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109604
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