Metabolism of arachidonic acid in ionophore-stimulated neutrophils. Esterification of a hydroxylated metabolite into phospholipids.

[14C]Arachidonic acid incubated with human neutrophils was esterified into phospholipids and triglycerides. Stimulation of these labeled neutrophils with ionophore A23187 (2 microM) results in release of [14C]arachidonate from phospholipid and its metabolism to prostaglandin E2 and 5-hydroxy-6,8,11,...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Stenson, W F, Parker, C W
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1979
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371295/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/387819/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109604
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