Participation of monocyte-macrophages and lymphocytes in the production of a factor that stimulates collagenase and prostaglandin release by rheumatoid synovial cells.

Cultured mononuclear cells from human peripheral blood produce a soluble factor (MCF) that stimulates collagenase and prostaglandin E2 (PGE2) release by cultured rheumatoid synovial cells up to several hundred fold. These target rheumatoid synovial cells lack conventional macrophage markers. To dete...

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Pubblicato in:	J Clin Invest
Autori principali:	Dayer, J M, Bréard, J, Chess, L, Krane, S M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1979
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371287/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/227933/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109596
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