Participation of monocyte-macrophages and lymphocytes in the production of a factor that stimulates collagenase and prostaglandin release by rheumatoid synovial cells.

Cultured mononuclear cells from human peripheral blood produce a soluble factor (MCF) that stimulates collagenase and prostaglandin E2 (PGE2) release by cultured rheumatoid synovial cells up to several hundred fold. These target rheumatoid synovial cells lack conventional macrophage markers. To dete...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Dayer, J M, Bréard, J, Chess, L, Krane, S M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1979
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371287/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/227933/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109596
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