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Activation of Arterial Matrix Metalloproteinases Leads to Vascular Calcification in Chronic Kidney Disease

BACKGROUND: The objective of the current study was to determine if altered regulation of matrix metalloproteinases (MMPs) may predispose to extracellular matrix degradation, facilitating arterial calcification in chronic kidney disease (CKD) using a progressive model of CKD-MBD, the Cy/+ rat. METHOD...

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Bibliografiske detaljer
Main Authors: Chen, Neal X., O'Neill, Kalisha D., Chen, Xianming, Kiattisunthorn, Kraiwiporn, Gattone, Vincent H., Moe, Sharon M.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712810/
https://ncbi.nlm.nih.gov/pubmed/21791917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000330175
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