Activation of Arterial Matrix Metalloproteinases Leads to Vascular Calcification in Chronic Kidney Disease

BACKGROUND: The objective of the current study was to determine if altered regulation of matrix metalloproteinases (MMPs) may predispose to extracellular matrix degradation, facilitating arterial calcification in chronic kidney disease (CKD) using a progressive model of CKD-MBD, the Cy/+ rat. METHOD...

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Detalhes bibliográficos
Main Authors: Chen, Neal X., O'Neill, Kalisha D., Chen, Xianming, Kiattisunthorn, Kraiwiporn, Gattone, Vincent H., Moe, Sharon M.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Original Report: Laboratory Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712810/
https://ncbi.nlm.nih.gov/pubmed/21791917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000330175
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