Succinate Dehydrogenase B Subunit Immunohistochemical Expression Predicts Aggressiveness in Well Differentiated Neuroendocrine Tumors of the Ileum

Immunohistochemical loss of the succinate dehydrogenase subunit B (SDHB) has recently been reported as a surrogate biomarker of malignancy in sporadic and familial pheocromocytomas and paragangliomas through the activation of hypoxia pathways. However, data on the prevalence and the clinical implica...

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Bibliographic Details
Main Authors: Milione, Massimo, Pusceddu, Sara, Gasparini, Patrizia, Melotti, Flavia, Maisonneuve, Patrick, Mazzaferro, Vincenzo, de Braud, Filippo G., Pelosi, Giuseppe
Format: Artigo
Language:Inglês
Published: MDPI 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712706/
https://ncbi.nlm.nih.gov/pubmed/24213468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers4030808
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