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Epidermal to Mesenchymal Transition and Failure of EGFR-Targeted Therapy in Glioblastoma

Glioblastoma multiforme (GBM), the most common primary brain tumor in adults, is almost never curable with the current standard treatment consisting of surgical resection, irradiation and temozolomide. The prognosis remains poor despite undisputable advances in the understanding of this tumor’s mole...

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Detalhes bibliográficos
Main Authors: Pala, Andrej, Karpel-Massler, Georg, Kast, Richard Eric, Wirtz, Christian Rainer, Halatsch, Marc-Eric
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712701/
https://ncbi.nlm.nih.gov/pubmed/24213322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers4020523
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