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Epidermal to Mesenchymal Transition and Failure of EGFR-Targeted Therapy in Glioblastoma

Glioblastoma multiforme (GBM), the most common primary brain tumor in adults, is almost never curable with the current standard treatment consisting of surgical resection, irradiation and temozolomide. The prognosis remains poor despite undisputable advances in the understanding of this tumor’s mole...

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Hlavní autoři: Pala, Andrej, Karpel-Massler, Georg, Kast, Richard Eric, Wirtz, Christian Rainer, Halatsch, Marc-Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712701/
https://ncbi.nlm.nih.gov/pubmed/24213322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers4020523
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