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Effect of (−)-trans-PAT, a novel 5-HT(2C) receptor agonist, on intake of palatable food in mice

(1R,3S)-(−)-trans-1-phenyl-3-dimethylamino-1,2,3,4-tetrahydronaphthalene (PAT) is a novel compound that has full-efficacy agonist activity at human 5-HT(2C) receptors and inverse agonist/antagonist activity at 5HT(2A) and 5HT(2B) receptors. In the present paper we describe its effects on food intake...

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Detalles Bibliográficos
Main Authors: Rowland, Neil E., Crump, Erica M., Nguyen, Nancy, Robertson, Kimberly, Sun, Zhuming, Booth, Raymond G.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712337/
https://ncbi.nlm.nih.gov/pubmed/18692085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.07.004
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