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Substance P downregulates expression of the high affinity IgE receptor (FcεRI) by human mast cells
The effect of the neuropeptide substance P (SP) on human mast cell (MC) phenotype is poorly understood. In this study, SP effects on human MC expression of the high affinity IgE receptor (FcεRI) were characterized. SP downregulated expression of FcεRI mRNA and protein by approximately 50% and in a c...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3712287/ https://ncbi.nlm.nih.gov/pubmed/20117843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2009.12.006 |
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