Prevalence of Neutralizing Antibodies to Adenoviral Serotypes 5 and 35 in the Adult Populations of The Gambia, South Africa, and the United States

One of the major limitations of the use of adenoviruses as gene therapy vectors is the existence of preformed immunity in various populations. Recent studies have linked failure of adenoviral gene therapy trials to the presence of antiadenoviral neutralizing antibodies (NAb). Understanding the distr...

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書目詳細資料
發表在:Clin Diagn Lab Immunol
Main Authors: Nwanegbo, Edward, Vardas, Eftyhia, Gao, Wentao, Whittle, Hilton, Sun, Huijie, Rowe, David, Robbins, Paul D., Gambotto, Andrea
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2004
主題:
Microbial Immunology
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371218/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15013987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CDLI.11.2.351-357.2004
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