Prevalence of Neutralizing Antibodies to Adenoviral Serotypes 5 and 35 in the Adult Populations of The Gambia, South Africa, and the United States

One of the major limitations of the use of adenoviruses as gene therapy vectors is the existence of preformed immunity in various populations. Recent studies have linked failure of adenoviral gene therapy trials to the presence of antiadenoviral neutralizing antibodies (NAb). Understanding the distr...

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Библиографические подробности
Опубликовано в: :Clin Diagn Lab Immunol
Главные авторы: Nwanegbo, Edward, Vardas, Eftyhia, Gao, Wentao, Whittle, Hilton, Sun, Huijie, Rowe, David, Robbins, Paul D., Gambotto, Andrea
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2004
Предметы:
Microbial Immunology
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371218/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15013987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CDLI.11.2.351-357.2004
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