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Combination of Obesity and High-Fat Feeding Diminishes Sensitivity to GLP-1R Agonist Exendin-4

Gastrointestinal mechanisms involved in the suppression of appetite are compromised in obesity. Glucagon-like peptide-1 (GLP-1) is released in response to nutrients, suppresses food intake, and has been shown to play a role in regulation of energy balance. It is not known whether obese-prone (OP) ra...

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Detalhes bibliográficos
Main Authors: Duca, Frank A., Sakar, Yassine, Covasa, Mihai
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712059/
https://ncbi.nlm.nih.gov/pubmed/23423571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1204
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