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Sustained Lipopolysaccharide-Induced Lung Inflammation in Mice Is Attenuated by Functional Deficiency of the Fas/Fas Ligand System

To determine whether the Fas/Fas ligand (FasL) (CD95/CD178) system contributes to the development of an inflammatory response in vivo, 2.5 μg of bacterial lipopolysaccharide (LPS; endotoxin) per g was administered intranasally to healthy mice (C57BL/6) and mutant mice deficient in either Fas (lpr mi...

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Bibliografiske detaljer
Main Authors: Matute-Bello, Gustavo, Winn, Robert K., Martin, Thomas R., Liles, W. Conrad
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC371192/
https://ncbi.nlm.nih.gov/pubmed/15013988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.11.2.358-361.2004
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