Fas (CD95) Induces Alveolar Epithelial Cell Apoptosis in Vivo : Implications for Acute Pulmonary Inflammation

Activation of the Fas/FasL system induces apoptosis of susceptible cells, but may also lead to nuclear factor κB activation. Our goal was to determine whether local Fas activation produces acute lung injury by inducing alveolar epithelial cell apoptosis and by generating local inflammatory responses...

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Main Authors: Matute-Bello, Gustavo, Winn, Robert K., Jonas, Mechthild, Chi, Emil Y., Martin, Thomas R., Liles, W. Conrad
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2001
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850249/
https://ncbi.nlm.nih.gov/pubmed/11141488
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