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CpG islands under selective pressure are enriched with H3K4me3, H3K27ac and H3K36me3 histone modifications

BACKGROUND: Histone modification is an epigenetic mechanism that influences gene regulation in eukaryotes. In particular, histone modifications in CpG islands (CGIs) are associated with different chromatin states and with transcription activity. Changes in gene expression play a crucial role in adap...

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Autores principales: Akhtar, Most Mauluda, Scala, Giovanni, Cocozza, Sergio, Miele, Gennaro, Monticelli, Antonella
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711888/
https://ncbi.nlm.nih.gov/pubmed/23837650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-13-145
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