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Melanocortin 4 Receptors Reciprocally Regulate Sympathetic and Parasympathetic - Preganglionic Neurons

Melanocortin 4 receptors (MC4Rs) in the central nervous system are key regulators of energy and glucose homeostasis. Notably, obese patients with MC4R mutations are hyperinsulinemic and resistant to obesity-induced hypertension. Although these effects are likely dependent upon the activity of the au...

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Autori principali: Sohn, Jong-Woo, Harris, Louise E., Berglund, Eric D., Liu, Tiemin, Vong, Linh, Lowell, Bradford B., Balthasar, Nina, Williams, Kevin W., Elmquist, Joel K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711728/
https://ncbi.nlm.nih.gov/pubmed/23374353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.12.022
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