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CBP80-Promoted mRNP Rearrangements during the Pioneer Round of Translation, Nonsense-Mediated mRNA Decay, and Thereafter

In mammalian cells, two different messenger ribonucleoproteins (mRNPs) serve as templates for protein synthesis. Newly synthesized mRNPs bound by the cap-binding protein heterodimer CBP80-CBP20 (CBC) initially undergo a pioneer round of translation. One purpose of this round of translation is to ens...

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Autors principals: Maquat, L.E., Hwang, J., Sato, H., Tang, Y.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711708/
https://ncbi.nlm.nih.gov/pubmed/21447822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2010.75.028
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