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High viral burden restricts short-lived effector cell (SLEC) number at late times postinfection through increased nTreg expansion()
Generating and maintaining a robust CD8(+) T cell response in the face of high viral burden is vital for host survival. Further, balancing the differentiation of effectors along the memory precursor effector cell (MPEC) vs. short-lived effector cell (SLEC) pathways may be critical in controlling the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711656/ https://ncbi.nlm.nih.gov/pubmed/23589620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200971 |
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