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Metastasis associated protein 1 and its short form variant stimulates Wnt1 transcription via promoting its derepression from Six3 corepressor

Although Wnt1 downstream signaling components have been well studied and activated in human cancer, the pathways that regulate Wnt1 itself have not been explored in-depth. Here we provide gain-of-function, loss-of function, and molecular evidence supporting functional interactions between metastasis...

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Autores principales: Kumar, Rakesh, Balasenthil, Seetharaman, Manavathi, Bramanandam, Rayala, Suresh K, Pakala, Suresh B
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711655/
https://ncbi.nlm.nih.gov/pubmed/20682799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0909
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