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Metastasis associated protein 1 and its short form variant stimulates Wnt1 transcription via promoting its derepression from Six3 corepressor

Although Wnt1 downstream signaling components have been well studied and activated in human cancer, the pathways that regulate Wnt1 itself have not been explored in-depth. Here we provide gain-of-function, loss-of function, and molecular evidence supporting functional interactions between metastasis...

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Hlavní autoři: Kumar, Rakesh, Balasenthil, Seetharaman, Manavathi, Bramanandam, Rayala, Suresh K, Pakala, Suresh B
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711655/
https://ncbi.nlm.nih.gov/pubmed/20682799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0909
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