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Peptide-Stimulation Enhances Compartmentalization and the Catalytic Activity of Lung Endothelial NOS

We reported that an 11 amino acid synthetic peptide (P1) activates lung endothelial cell nitric oxide synthase (eNOS) independent of its change in expression and/or phosphorylation. Since caveolae/eNOS dissociation is known to enhance the catalytic activity of eNOS, we examined whether P1-mediated i...

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Autors principals: Hutchinson, Tarun E., Kuchibhotla, Sudeep, Block, Edward R., Patel, Jawaharlal M.
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711584/
https://ncbi.nlm.nih.gov/pubmed/19910687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000257487
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