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Force-plate quantification of progressive behavioral deficits in the R6/2 mouse model of Huntington’s disease
The R6/2 mouse is a popular model of Huntington’s disease (HD) because of its rapid progression and measurable behavioral phenotype. Yet current behavioral phenotyping methods are usually univariate (e.g., latency to fall from a rotarod) and labor intensive. We used a force-plate actometer and speci...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711515/ https://ncbi.nlm.nih.gov/pubmed/19447289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2009.03.022 |
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