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Human mitochondrial disease-like symptoms caused by a reduced tRNA aminoacylation activity in flies

The translation of genes encoded in the mitochondrial genome requires specific machinery that functions in the organelle. Among the many mutations linked to human disease that affect mitochondrial translation, several are localized to nuclear genes coding for mitochondrial aminoacyl-transfer RNA syn...

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Detalhes bibliográficos
Main Authors: Guitart, Tanit, Picchioni, Daria, Piñeyro, David, Ribas de Pouplana, Lluís
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711456/
https://ncbi.nlm.nih.gov/pubmed/23677612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt402
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