Ewing tumors that do not over-express BMI-1 are a distinct molecular subclass with variant biology: A report from the Children’s Oncology Group

PURPOSE: Ewing sarcoma family tumors (ESFT) are aggressive tumors of putative stem cell origin for which prognostic biomarkers and novel treatments are needed. In several human cancers high expression of the polycomb protein BMI-1 is associated with poor outcome. We have assessed the potential clini...

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Detalhes bibliográficos
Main Authors: Cooper, Aaron, van Doorninck, John, Ji, Lingyun, Russell, Darren, Ladanyi, Marc, Shimada, Hiroyuki, Krailo, Mark, Womer, Richard B., Hsu, Jessie Hao-ru, Thomas, Dafydd, Triche, Timothy J., Sposto, Richard, Lawlor, Elizabeth R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711406/
https://ncbi.nlm.nih.gov/pubmed/21047978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1417
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