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BMI-1 promotes Ewing sarcoma tumorigenicity independent of CDKN2A-repression
Deregulation of the polycomb group gene BMI-1 is implicated in the pathogenesis of many human cancers. In this study, we have investigated if the Ewing's Sarcoma Family of Tumors (ESFT) express BMI-1 and whether it functions as an oncogene in this highly aggressive group of bone and soft tissue...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2570201/ https://ncbi.nlm.nih.gov/pubmed/18701473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6152 |
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