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BMI-1 promotes Ewing sarcoma tumorigenicity independent of CDKN2A-repression

Deregulation of the polycomb group gene BMI-1 is implicated in the pathogenesis of many human cancers. In this study, we have investigated if the Ewing's Sarcoma Family of Tumors (ESFT) express BMI-1 and whether it functions as an oncogene in this highly aggressive group of bone and soft tissue...

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Detalhes bibliográficos
Main Authors: Douglas, Dorothea, Hsu, Jessie Hao-Ru, Hung, Long, Cooper, Aaron, Abdueva, Diana, van Doorninck, John, Peng, Grace, Shimada, Hiro, Triche, Timothy J., Lawlor, Elizabeth R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570201/
https://ncbi.nlm.nih.gov/pubmed/18701473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6152
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