Parathyroid Hormone (PTH)/PTH-related Peptide Type 1 Receptor (PPR) Signaling in Osteocytes Regulates Anabolic and Catabolic Skeletal Responses to PTH

Parathyroid hormone (PTH) is the only Food and Drug Administration-approved anabolic agent to treat osteoporosis; however, the cellular targets of PTH action in bone remain controversial. PTH modulates bone turnover by binding to the PTH/PTH-related peptide (PTHrP) type 1 receptor (PPR), a G-protein...

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Détails bibliographiques
Auteurs principaux: Saini, Vaibhav, Marengi, Dean A., Barry, Kevin J., Fulzele, Keertik S., Heiden, Erica, Liu, Xiaolong, Dedic, Christopher, Maeda, Akira, Lotinun, Sutada, Baron, Roland, Pajevic, Paola Divieti
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
Sujets:
Molecular Bases of Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711281/
https://ncbi.nlm.nih.gov/pubmed/23729679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.441360
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