Zoledronic Acid Reverses the Epithelial-Mesenchymal Transition and Inhibits Self-Renewal of Breast Cancer Cells through Inactivation of Nuclear Factor kappa B

Zoledronic acid (ZA), a third generation bisphosphonate, has been shown to reduce cell migration, invasion, and metastasis. However, the effects of ZA on the epithelial-mesenchymal transition (EMT), a cellular process essential to the metastatic cascade, remain unclear. Therefore, the effects of ZA...

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Main Authors: Schech, Amanda J., Kazi, Armina A., Gilani, Rabia A., Brodie, Angela H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711266/
https://ncbi.nlm.nih.gov/pubmed/23619300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0304
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https://ncbi.nlm.nih.gov/pmc/articles/PMC3711266/
https://ncbi.nlm.nih.gov/pubmed/23619300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0304