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An Electrophoretic Mobility Shift Assay Identifies a Mechanistically Unique Inhibitor of Protein Sumoylation

The dynamic, posttranslational modification of proteins with a SUMO tag has been recognized as an important cellular regulatory mechanism relevant to a number of cancers as well as normal embryonic development. As part of a program aimed towards the identification of inhibitors of SUMO conjugating e...

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Autors principals: Kim, Yeong Sang, Nagy, Katelyn, Keyser, Samantha, Schneekloth, John S.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711074/
https://ncbi.nlm.nih.gov/pubmed/23601649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.04.001
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